Nevertheless, evidence on whether grapefruit juice lowers the risk of kidney stones seems to be mixed. The review explains that citrus juices aid hydration by promoting fluid intake, alkalinizing urine despite being acidic, and by being rich in citrate, the go-to inhibitor of stone formation.
Fortunately, research suggests that since grapefruit juice is a citrus juice, it may help reduce the risk of kidney stones. Overall, people at risk of vitamin C deficiency include smokers, people who are fighting infections, are obese, or have type 2 diabetes, and athletes or people who exercise excessively.Īccording to a 2021 review published in the journal Nutrients, the basics for kidney stone prevention include proper hydration, preventing an overload of oxalate and uric acid in the urine (two of the four substances that lead to stone formation), alkalinization of urine to avoid acidic urine, and promoting high urinary citrate levels. However, the study also states that vitamin C deficiency is the fourth leading nutrient deficiency in the United States, and that some people may either need to consume higher amounts or generally have lower levels of the vitamin in their system. For instance, it promotes the mobilization of white blood cells (your body's defense cells) to the site of infection to help fight harmful microorganisms, enhances microbial killing, helps avoid and treat respiratory infections, and supports your skin's barrier function against disease-causing organisms such as bacteria or viruses. Once ingested, it boosts your immune system via multiple pathways, per a 2017 study published in the journal Nutrients.
Since vitamin C is an essential vitamin - meaning that your body can't produce it - you must get your daily dose from foods. Thus, be sure to consult with your doctor about whether or not grapefruit juice affects your medication. Furthermore, the effects may last up to 3 days after drinking the juice (via Healthline). On the other hand, the juice can also keep certain medications from being absorbed, leading to a lower dose and preventing the drug from working correctly.Īccording to a 2013 study published in the Canadian Medical Association Journal, grapefruit can interact with more than 85 drugs, including certain antibiotics, cholesterol-lowering, blood pressure-lowering, anti-organ-transplant rejection, anti-anxiety, anti-cancer, pain-relieving, anti-inflammatory, and HIV drugs. If your body ends up with a higher dose than it can handle, you may experience more side effects, including tissue damage and organ failure. However, as with many things in life, more does not always equal better. Thus, instead of being metabolized, the drug remains available in your bloodstream for longer. This happens because grapefruit juice blocks the activity of an enzyme called CYP3A4, which helps break down certain drugs. When grapefruit juice enhances a drug, it means that it allows higher doses of the drug to enter your system.
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